Mexico halts some vaccinations after 2 children die, 29 are hospitalized - LA Times
Excerpt:
Mexico stopped administering certain vaccines nationwide and launched an investigation into why two children died and 29 fell ill this weekend after receiving inoculations in Chiapas, the country’s southernmost state, officials said.
A total of 52 children in the municipality of Simojovel received vaccines against tuberculosis, rotavirus and hepatitis B on Friday, and 31 of them had adverse reactions that night, according to the Mexican Institute for Social Security. Of the hospitalized children, six are in grave condition and 23 are stable, the health agency said.
The hypocricy of Reagan
https://medium.com/federalists/embracing-reagans-notion-of-small-government-federalism-dde83edd11bb
"Reagan’s vision of modern Federalism is to achieve the same goals of the original Federalists but from the opposite end of the spectrum. He realized that the national government was quickly becoming too powerful. He embraced the Federalist approach of checks and balances between the states and Washington DC that empowers either to properly represent their citizens. If someone in Michigan was being oppressed by the federal government, they could go to the state to seek protections. If it was Michigan that was oppressing this person, they could call on DC for help. Only through balance of powers can this country be properly managed. Only through balance of powers can the people’s freedoms be properly protected."
Another antivaccine paper bites the dust by David Gorski
Another antivaccine paper bites the dust by David Gorski
Excerpt:
I've written on quite a few occasions about a pair of scientists beloved by the antivaccine movement. I'm referring, of course, to Christopher Shaw and Lucija Tomljenovic. Whether it is their publishing dubious "evidence" that HPV vaccines cause premature ovarian failure or even death or demonizing aluminum as a vaccine adjuvant, Shaw and Tomljenovic publish nothing but antivaccine pseudoscience that antivaxers love to cite whenever they dump some turd of a study on the medical literature.
Just last month, they dumped their latest turd of a study, in which they basically tortured mice in the name of pseudoscience. Later, after I wrote my first analysis of the study in which I described how poorly designed and executed the experiments were, I discovered that there's more than just bad science there. There's possible fraud, as circulating on PubPeer are reports of image manipulation that are quite convincing. At the time this rather obvious image manipulation was being discussed, so, too, was the possibility of retraction. After all, if there's one thing that merits pretty much an automatic retraction in science, it's manipulation of images presented as data in a scientific paper.
Not surprisingly, then, yesterday I learned from Retraction Watch that Shaw and Tomljenovic's latest paper will be retracted as well. The editor of the Journal of Inorganic Biochemistry announced that the journal will be retracted:
The journal’s editor, John Dawson of the University of South Carolina, told Retraction Watch:The paper by Shaw and co-workers is being retracted jointly by the authors and the editor.He noted there will be a “statement accompanying the retraction of the paper.”Shaw told us that his lab began investigating the issues raised on PubPeer “within a day” and reported its findings to both UBC and the journal soon after. He said:Our own analysis showed some figures had been altered. We requested a retraction because we could not understand how that had happened. We felt the data had been compromised.Shaw said that the problems mostly lie with data showing no change in gene or protein expression levels after aluminum injections — but also with some data showing changes in expression, which the paper attributed to the injections.
Next up, Shaw tries to pass the buck:
Shaw said that first author Dan Li, a former postdoc who performed the molecular biology and gene expression analysis for the study, has agreed to the retraction but not yet offered an official explanation about the data. Shaw told us:She denied that anything had been manipulated, or that anything was amiss.He added that when Li left the lab in 2015, she took the original data with her:UBC policy is that original data never leave the lab. We’ve asked for them to be returned to us.Shaw said he thinks the core data are “probably correct,” but said he plans to have the experiments re-done:It is what it is. We’ve done everything we can on our end. We’re still having conversations with Li on where the data are and how we get them back. That’s as much as we can do at this point.
I suppose that it's possible that Shaw was duped by a postdoctoral fellow in his laboratory. When you're the head of a lab and the principal investigator of a study, you tend to come to trust those working for you. You don't want to think that one of them might be committing scientific fraud by manipulating images. On the other hand, as PI, one has to be on guard for this very thing. The PI is basically the captain of the ship, and the buck stops at his desk, and whatever other cliche you want to invoke to say that he is in charge and responsible for the integrity of the data produced by his lab.
The kindest possible interpretation is that Christopher Shaw runs a loose ship, so loose that he didn't notice that many of the bands on the images of his DNA gels and the autoradiographs of his Western blots were duplicated, flipped, and otherwise manipulated. Certainly, letting the raw data and raw images out of the lab is not good lab practice, particularly in this day and age, when pretty much all images of gels and Western blots are recorded digitally. In my lab, for instance, there is a lab shared drive, and every single image generated is stored there, so that original images used to make figures can always be recovered. PRanoid PI that I am, I even periodically copy the whole shared drive to my own computer, which in turn is regularly backed up. Key figures are preserved on cloud drives.
The worst possible interpretation is that Shaw either knew about the image manipulation (or even ordered it) or that he put so much pressure on his postdoc to produce results that she felt that she had to falsify figures to produce what he wanted. Of course, I wonder about Shaw's practices. For instance, in my discussion of the image manipulation, I noted that Shaw and Tomljenovic have at minimum engaged in self-plagiarism, recycling figures from a 2014 review article into which they dumped a little original data in their soon-to-be retracted paper. So, in terms of commonly accepted practices, we already know Shaw's rather...unconcerned.
read Another antivaccine paper bites the dust by David Gorski
So how much money do doctors really make from vaccines?
Excerpts:
So how much money do doctors really make from vaccines? The average American pediatrician has 1546 patients, though some pediatricians see many more. The vast majority of those patients are very young, perhaps because children transition to a family physician or stop visiting the doctor at all as they grow up. As they table above explains, Blue Cross Blue Shield pays pediatricians $400 per fully vaccinated child. If your pediatrician has just 100 fully-vaccinated patients turning 2 this year, that’s $40,000. Yes, Blue Cross Blue Shield pays your doctor a $40,000 bonus for fully vaccinating 100 patients under the age of 2. If your doctor manages to fully vaccinate 200 patients, that bonus jumps to $80,000.
But here’s the catch: Under Blue Cross Blue Shield’s rules, pediatricians lose the whole bonus unless at least 63% of patients are fully vaccinated, and that includes the flu vaccine. So it’s not just $400 on your child’s head–it could be the whole bonus. To your doctor, your decision to vaccinate your child might be worth $40,000, or much more, depending on the size of his or her practice.
Explains why they push so hard on flu vaccine.
Court Awards $137,500 After 8 Vaccines Kills Infant In Just 12 Hours by Melissa Curtin
Excerpt:
Kara Krause tragically lost her baby girl, Peyton, 12 hours after being injected with eight vaccines in 2008. Through the National Vaccine Injury Compensation Program (NVICP) and Special Master’s “Vaccine” Court, it was proven the DTaP, Hib, Hepatitis B, PCV, IPV, and Rotavirus vaccines killed her daughter. Kara describes her darling daughter, “She was a normal, happy, healthy baby. I still hear her little sounds so clearly. She was my first true love.”
Kara discloses her painful story below to educate others before they make a decision to vaccinate: “I’m hoping it will at least reach someone allowing them to do their own research and not rely on doctors alone.”
Kara: I lost my daughter Peyton at 6 weeks old, approximately 12 hours after receiving her two month vaccinations, when she was a month and 12 days old. She was given eight total vaccines, [DTaP/ IPV (Polio)/ Hep B (Pediarix), Pneumococcal conjugate (Prevnar), Hib, and Rotavirus (Rotateq)]. According to the autopsy report and medical examiner, her death was classified as “Sudden Unexplained Death in Infancy (SUDI).”
Almost two years after her death, I was told about the NVICP (National Vaccination Injury Compensation Program). This is a “non-fault” government-run program funded by a tax on the vaccines. It acts as an insurance policy to protect vaccine manufacturers from being sued for vaccination related deaths and injuries. Their cases go to trial as any other court cases, but they are overseen by a Special Master, not a jury. The Special Master hears both the victim and government’s arguments. If, and only if, proven scientific data or testimony (not a casual link or circumstance) is presented by the plaintiffs, the master then decides on the amount of compensation to be awarded to the victim or their family.
Big Pharma Plays Hide-the-Ball With Data by BEN WOLFORD
Excerpts
On the morning of March 2, 2005, a 14-year-old Japanese girl woke up scared. At first she thought someone was outside the house watching her, but then she decided the stranger must be inside. She wandered restlessly and, despite the cold weather, threw open all the windows. Later, over a meal, she declared, "The salad is poisoned." Two days later, she said she wanted to kill herself.
That Japanese girl, whose case was detailed in an FDA report, did not kill herself. But at least 70 people have died, many of them by suicide, after Tamiflu-induced episodes. The deaths were almost surreal: A 14-year-old who took Tamiflu jumped off a balcony, and a 17-year-old on the drug ran in front of a truck. Scientists documented other cases of "psychopathic events," including a South Korean girl who temporarily developed bipolar disorder and an 8-year-old Japanese boy who wouldn't answer to his name and began to growl.
...
But evidence released earlier this year by Cochrane Collaboration, a London-based nonprofit, shows that a significant amount of negative data from the drug's clinical trials were hidden from the public.
...
The most infamous case of publication bias is a 1980 study in which heart attack patients were split into two groups: One group received a drug called lorcainide, while the other group received a placebo. Researchers wanted to find out whether lorcainide cures dangerous abnormal heart rhythms, which it does. But during the study, nine of the lorcainide patients died, compared with just one of the placebo patients. Lorcainide's maker stopped production soon after for unrelated commercial reasons, and consequently the researchers never published their report. They believed the deaths to be "an effect of chance."
But physicians continued prescribing drugs similar to lorcainide. Finally, in 1993, the researchers apologized for withholding the study, which they said could have "provided an early warning of trouble ahead." But the damage was done: Throughout the '80s, an estimated 20,000 to 75,000 people died in the U.S. each year from the inappropriate prescription of antiarrhythmic drugs, according to a 2003 editorial by Kay Dickersin and Drummond Rennie in The Journal of the American Medical Association.
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